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SeroTropin© is one of the most potent recombinant Human Growth Hormones on the market today. It's 191 amino acid sequence HGH (natural to human body) and is produced by Vetruvia Pharmaceuticals. GHT, an internationally recognized marketing firm, reports that SeroTropin© has become one of the world’s top producers of HGH behind EMD Serono Serostim. But, SeroTropin© 8mg dosing makes it one of the most potent HGH formulas on the market. We only produce SeroTropin© in a 200iu presentation to ensure that the patient has adequate resources to encompass their needs.
SeroTropin© stimulates linear growth and increases growth rate in children who lack adequate endogenous growth hormone. In adults with growth hormone deficiency, SeroTropin© reduces fat mass, increases muscle mass and improves energy, vitality and subjective well-being. In patients suffering from severe burns, AIDS associated muscle wasting, or undergoing major operations, SeroTropin© promotes wound healing, attenuates the protein-catabolic response and improves whole-body nitrogen economy after operation. Bodybuilders use SeroTropin© because it promotes growth of new muscle cells and uses body's own fat as energy source.
Vetruvia has recently concluded all research and development and testing of SeroTropin©. Manufacturing was started in November 2010. Set apart from all HGH manufacturers, SeroTropin© and the patent pending ‘CPF Technology’ is the future of all HGH. Over 3 years of testing on Crystallized Powder Formation and traditional Wafer Powder Formation (disc) has been extensively analyzed and the conclusions are tremendous. CPF allows a longer usage time frame, it maintains purity and effectiveness. WPF is used in all other HGH products to increase shelf-life and upon re-constitution it results in a 25-30% breakdown of the vital amino acids that make HGH effective. SeroTropin© is FDA Approved and will be the leader in HGH manufacturing.
Release of growth hormone
The growth hormones in circulation in the body are bound to a protein (growth hormone binding protein, GHBP), that are derived from the growth hormone receptor. The growth hormones are secreted in the blood by the somatotrope cells of the anterior pituitary gland in large amount than any other pituitary hormone.
During puberty the secretions level is very high, and the transcription factor PT1, (a protein that works with other proteins to either promote or suppress the transcription of genes), stimulates the development of these cells to produce growth hormone. If these cells fails to develop as well the destruction in the anterior pituitary glands, a growth hormone deficiency results.
Structure and gene of molecule
Human growth hormones have their genes localized in the q22-24 region of chromosome 17 (GH1) which are closely related to human chorionic somatomammotropin (hCS, also known as placental lactogen) genes.
Human growth hormone (HGH), human chorionic somatomammotropin (hCS), and prolactin (PRL) are a group of homologous hormones with have growth-promoting and lactogenic activity. The human growth hormone is a protein of 191 amino acids, having a molecular weight of 22,000 Daltons,
Functions of growth hormone
Growth hormone (GH) acts by interacting with specific receptors on the surface of the cells. Increase in height is one of the best known effects of growth hormone (GH) actions in children and it is stimulated by two mechanisms.
Growth hormone directly stimulates division and multiplication of chondrocytes of cartilage. These are primarily the cells in the growing ends (epiphyses) of children long bones (arms, legs, digits). Also, growth hormone also stimulates production of insulin-like growth factor 1 (IGF-1, a hormone homologous to proinsulin. The major target organ of growth human for this process is the liver, and is the primary region of production of IGF-1. The insulin-like growth factor IGF-1 has growth stimulating effects on varieties of tissues.
Growth hormone deficiency
Deficiencies of growth hormone differs at various ages; children with growth deficiencies have short stature while in adults the effects of the deficiencies are not easily noticeable and may include decrease in strength, energy, and bone mass as well as increased cardiovascular risk.
Other causes of growth deficiencies include mutations of specific genes, congenital malformations involving the hypothalamus or pituitary gland, and damages to the pituitary gland from injury, surgery or disease.
Growth hormone replacement
Human growth hormone deficiencies are treated by replacing growth hormone. All the growth hormone presently in use is a biosynthetic version of human growth hormone, manufactured by recombinant DNA technology.
Since growth hormone is a large protein molecule, it must be injected into subcutaneous tissue (or muscles) to get it into the blood. A patient having a long-standing deficiency of growth, the benefits derived from the treatment are dramatic and gratifying and side effects are rare. Growth hormone treatment is a replacement therapy in adults with GH deficiency of either childhood-onset (after completing growth phase) or adult-onset (usually as a result as result of acquired pituitary tumor).
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